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Protego Bio

Biotech & Life Sciences · San Diego, United States · Founded 2011

Protein stabilizing therapies targeting misfolding diseases MoreLess

Protego Biopharma is a biotechnology startup that is pioneering the discovery and development of innovative therapeutics to treat protein misfolding diseases. The company operates in the pharmaceutical industry, specifically in the drug discovery sector. Its primary focus is on systemic amyloid diseases like light chain (LC) amyloidosis and other monogenetic protein misfolding diseases that cause a variety of health issues including myopathy, cardiomyopathy, stroke, renal disease, retinal diseases, channelopathies, and various degenerative diseases.

Protego Biopharma's business model revolves around the use of advanced bioinformatics, deep biology, and clinical path analysis to identify high-confidence targets for drug development. The company's approach is data-driven and focuses on modifying diseases through an innovative discovery platform. They also use specific and sensitive biomarkers for early patient identification and to measure therapeutic efficacy.

The company's revenue model is likely based on the development and commercialization of its therapeutics. Once a drug is developed, it can be patented and sold to healthcare providers or directly to patients. Additionally, the company may generate income through partnerships or collaborations with other pharmaceutical companies.

The company was co-founded by Dr. Jeffery W. Kelly and Dr. Richard Labaudinière, who have previously demonstrated success in this field with the discovery and development of tafamidis, a drug used for the treatment of transthyretin amyloidosis.

Keywords: Biotechnology, Drug Discovery, Protein Misfolding Diseases, Systemic Amyloid Diseases, Bioinformatics, Disease Modifying, Biomarker Discovery, Precision Medicine, Pharmacological Chaperones, Therapeutics.

Company overview

Protego Bio company information

The essential company record, classifications and operating signals in one place.

Status
Operational
Founded
2011
Headquarters
San Diego, United States
Employees
26
Open positions
3
Dealroom signal
41.3
sub industryBioTechnologysub industryHealth Platformbusiness modelManufacturingindustryHealthsectorBiotechnologysectorDrug DevelopmentsectorSpinoutsectorTech for Biotech and PharmasectorBiotech and PharmasectorproteomicssectorDT and LSsectorscience-basedclient focusb2b

Valuation & funding

Protego Bio funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SERIES BOther financing Dec 2025 $130M $520M Lightspeed Venture Partners · MPM BioImpact · Digitalis Ventures · Scripps Translational Science Institute
SERIES AOther financing Nov 2021 $51M $204M Lightspeed Venture Partners · MPM BioImpact · Vida Ventures
SPINOUTOther financing Jan 2011 $0 Scripps Translational Science Institute
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Growth signals

Protego Bio website traffic

Latest recorded traffic for Protego Bio is 2.1K monthly website visits, down 8.7% over the last three months. Protego Bio's team grew 4% over the past year.

Latest monthly visits2.1K 3-month web change-8.7% 1-year team growth+4%
Monthly website visits55 observations · Oct 2021–Jul 2026
Hover or focus a point to see its exact monthly valueCompare with peers →

Comparisons

Protego Bio compared with similar companies

Dealroom’s weighted taxonomy model identifies the closest operating peers. Company identity and context stay open; selected comparison metrics preview what is available in the platform.

CompanyHeadquartersStatusEmployeesTotal fundingValuation
PlexiumA drug development startup that leverages techniques from various physical-science and computational disciplines San Diego, United States Operational 33 $225M $510M
Stablix TherapeuticsStablix | Protein Stabilization Therapeutics New York City, United States Operational
Sibylla BiotechFacing the complexity of drug discovery with the power of an innovative approach for meeting unmet medical needs Bresso, Italy Operational
Relay TherapeuticsA new breed of company at the intersection of computation and biotechnology that is committed to creating medicines that will have a transformative impact on patients Cambridge, United States Operational
ArzedaDevelops enzyme design technology to create entirely novel designer cell factories capable of industry-scale chemical production Seattle, United States Operational
NeuroKaireGenetika+ is developing a tailored medical diagnostic instrument to help doctors cure depression. Genetika+ predicts the best pharmacological treatment for each patient, allowing faster treatment Kearny, United States Operational
Amphista TherapeuticsNext-generation therapeutics for targeted protein degradation Great Abington, United Kingdom Operational
DrugBankAI-powered pharmaceutical knowledge platform for drug development Edmonton, Canada Operational
Showing 8 of the closest matchesCompare every metric →

Talent graph

Protego Bio's talent

Book a demo to see the people
Team profiled 2 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

10 investors on Protego Bio's cap table

Sourced from Dealroom's funding and investor records. Investor profile links are shown where available.

Series A 10 investors entered at this stage
Lightspeed Venture Partners
MPM BioImpact
Vida Ventures
Novartis Venture Fund
Forbion Capital Partners
Digitalis Ventures
Scripps Translational Science Institute
YK Bioventures
Omega Funds
Droia Oncology Ventures

Global footprint

Where Protego Bio has talent and traffic

Workforce by country
3 countries with
team presence
🇺🇸 United States89.5%
🇳🇱 Netherlands5.3%
🇩🇪 Germany5.3%
3 countries shown

In the news

Latest news about Protego Bio

Recent press, funding announcements, and product moves mentioning Protego Bio — open to read from the original sources.

See all news

Market sentiment

What the market is saying about Protego Bio

An AI-synthesized read of the highest-engagement posts about Protego Bio on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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