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Plexium

Biotech & Life Sciences · San Diego, United States · Founded 2017

A drug development startup that leverages techniques from various physical-science and computational disciplines MoreLess

Plexium is a biotech startup that operates in the field of targeted protein degradation (TPD), a promising area of drug discovery. The company's primary focus is on the development of next-generation TPD drugs that can target and degrade disease-causing proteins in the body. These drugs have potential applications in a wide range of therapeutic areas, including cancer and other serious diseases.

Plexium's unique selling point is its proprietary high-throughput cell-based screening technology. This technology allows the company to rapidly test and identify compounds that can degrade target proteins in a disease-relevant environment. This accelerates the drug discovery process and increases the chances of finding effective treatments.

The company's business model revolves around the development and commercialization of its TPD drugs. Plexium generates revenue through the sale of these drugs once they have been approved by regulatory bodies. Additionally, the company also partners with other biotech and pharmaceutical companies to develop and commercialize new drugs, providing another source of income.

Plexium's clients are primarily patients suffering from diseases that can be treated with TPD drugs. However, the company also serves the broader medical community by providing new treatment options and contributing to the advancement of medical science.

In summary, Plexium is a pioneering biotech company that is pushing the boundaries of targeted protein degradation to improve lives. Its unique technology and innovative approach to drug discovery make it a promising player in the biotech industry.

Keywords: Biotech, Targeted Protein Degradation, Drug Discovery, High-Throughput Screening, Cancer Treatment, Serious Diseases, Drug Development, Drug Commercialization, Medical Science, Biotech Partnerships.

Company overview

Plexium company information

The essential company record, classifications and operating signals in one place.

Status
Operational
Founded
2017
Headquarters
San Diego, United States
Employees
36
Open positions
None listed
Dealroom signal
63.0
sub industryBioTechnologysub industryHealth Platformbusiness modelManufacturingindustryHealthsectorBiotechnologysectorOncologysectorDrug DevelopmentsectorSpinoutsectorTech for Biotech and PharmasectorBiotech and PharmasectorproteomicssectorDT and LSsectorscience-basedclient focusb2b

Valuation & funding

Plexium funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
LATE VCOther financing Aug 2025 $60M $510M Undisclosed
LATE VCOther financing Feb 2022 $102M $408M CRV · Pivotal Life Sciences · Neotribe · M Ventures
LATE VCOther financing Jan 2021 $35M $140M Lux Capital · DCVC · The Column Group · Pivotal Life Sciences
SERIES AOther financing Oct 2019 $28M $112M CRV · The Column Group · M Ventures
SERIES AOther financing Apr 2019 DCVC
SEEDOther financing Oct 2018 DCVC
SEEDOther financing Feb 2018 CRV
SPINOUTOther financing Aug 2017 Scripps Translational Science Institute
Showing 8 recorded eventsUnlock the complete deal history →

Growth signals

Plexium website traffic

Latest recorded traffic for Plexium is 5.7K monthly website visits, up 111.1% over the last three months. Plexium's team declined 29.4% over the past year.

Latest monthly visits5.7K 3-month web change+111.1% 1-year team growth-29.4%
Monthly website visits88 observations · Dec 2018–Jul 2026
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Comparisons

Plexium compared with similar companies

Dealroom’s weighted taxonomy model identifies the closest operating peers. Company identity and context stay open; selected comparison metrics preview what is available in the platform.

Showing 8 of the closest matchesCompare every metric →

Talent graph

Plexium's talent

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Team profiled 23 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

14 investors on Plexium's cap table

Sourced from Dealroom's funding and investor records. Investor profile links are shown where available.

Seed 2 investors entered at this stage
Series A 2 investors entered at this stage
The Column Group
M Ventures
Series B+ 9 investors entered at this stage
Lux Capital
Pivotal Life Sciences
Neotribe
TCGX
SoftBank
Pappas Capital
BVF Partners
RA Capital Management
Surveyor Capital
Other known 1 additional known investor
Scripps Translational Science Institute

Global footprint

Where Plexium has talent and traffic

Workforce by country
3 countries with
team presence
🇺🇸 United States95.1%
🇩🇪 Germany2.4%
🇬🇧 United Kingdom2.4%
3 countries shown

In the news

Latest news about Plexium

Recent press, funding announcements, and product moves mentioning Plexium — open to read from the original sources.

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Market sentiment

What the market is saying about Plexium

An AI-synthesized read of the highest-engagement posts about Plexium on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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