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Mendra

Biotech & Life Sciences · San Francisco, United States · Founded 2025

AI-powered therapeutic acquisition and commercialization for rare diseases MoreLess

Mendra is a biopharmaceutical company that launched in January 2026, focusing on advancing therapies for rare diseases by utilizing artificial intelligence. The company was founded in 2025 by 8VC and 5AM Ventures. Mendra aims to acquire, develop, and commercialize treatments for rare diseases with high unmet needs.

The company's business model centers on using AI to modernize and accelerate the drug development process. This includes leveraging AI for asset selection, patient identification, speeding up clinical trial enrollment, and facilitating access to global markets. To fund these operations, Mendra announced an oversubscribed $82 million Series A financing round at its launch. The round was co-led by OrbiMed, 8VC, and 5AM Ventures, with participation from Lux Capital and Wing VC. These funds are allocated to acquire and develop the initial rare disease assets for the company's portfolio.

Mendra is led by a management team with extensive experience in the biopharmaceutical and AI sectors. The co-founder and CEO, Joshua Grass, has over 20 years of leadership experience, including his time at BioMarin Pharmaceutical where he was key in building its rare disease portfolio, and successful exits as CEO of Modis Therapeutics and Escient Pharmaceuticals. He is joined by co-founder and Chief Technology Officer Lalarukh Haris Shaikh, Ph.D., who previously served as an Executive Vice President at Palantir Technologies, and Chief Commercial Officer Jeff Ajer, a former CCO at BioMarin.

Keywords: biopharmaceutical, rare diseases, artificial intelligence, drug development, clinical trials, therapeutics, commercialization, Series A, venture capital, patient identification, asset acquisition, global markets, OrbiMed, 8VC, 5AM Ventures, Joshua Grass, BioMarin, Palantir Technologies, Lalarukh Haris Shaikh, Jeff Ajer

Company overview

Mendra company information

The essential company record, classifications and operating signals in one place.

Status
Operational
Founded
2025
Headquarters
San Francisco, United States
Employees
9
Open positions
None listed
Dealroom signal
59.0
sub industryPharmaceuticalsub industryBioTechnologybusiness modelManufacturingindustryHealthsectorBiotechnologysectorDrug DevelopmentsectorChronic DiseasesectorBiotech and PharmasectorAI Drug DiscoverysectorRare DiseasessectorDT and LSsectorscience-basedclient focusb2btechnologyArtificial Intelligence

Valuation & funding

Mendra funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SERIES AOther financing Jan 2026 $82M $328M Lux Capital · 5AM Ventures · OrbiMed · 8VC
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Growth signals

Mendra website traffic

Latest recorded traffic for Mendra is 940 monthly website visits, up 308.7% over the last three months.

Latest monthly visits940 3-month web change+308.7%
Monthly website visits7 observations · Jan 2026–Jul 2026
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Comparisons

Mendra compared with similar companies

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Showing 8 of the closest matchesCompare every metric →

Talent graph

Mendra's talent

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Team profiled 2 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

5 investors on Mendra's cap table

Sourced from Dealroom's funding and investor records. Investor profile links are shown where available.

Series A 5 investors entered at this stage
5AM Ventures
OrbiMed
8VC
Lux Capital
Wing Venture Capital

Global footprint

Where Mendra has talent and traffic

Workforce by country
2 countries with
team presence
🇺🇸 United States75%
🇬🇧 United Kingdom25%
2 countries shown

In the news

Latest news about Mendra

Recent press, funding announcements, and product moves mentioning Mendra — open to read from the original sources.

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Market sentiment

What the market is saying about Mendra

An AI-synthesized read of the highest-engagement posts about Mendra on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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