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Splisense

Biotech & Life Sciences · Jerusalem, Israel · Founded 2016

Developing transformative RNA-based treatments for unmet needs relating to CF and other genetic pulmonary illnesses MoreLess

SpliSense is a clinical-stage biotechnology company focused on developing transformative RNA-based treatments for unmet needs in diverse pulmonary diseases. Utilizing clinically validated Antisense Oligonucleotide (ASO) technology, SpliSense delivers its treatments non-invasively by inhalation directly to the lungs. The company is engaged in various stages of drug development, from discovery to Investigational New Drug (IND) applications. SpliSense primarily serves patients suffering from severe pulmonary conditions such as Cystic Fibrosis (CF) and Idiopathic Pulmonary Fibrosis (IPF). The company's business model revolves around the research, development, and commercialization of its innovative therapies. Revenue is generated through partnerships, licensing agreements, and eventual sales of approved treatments.

Keywords: RNA-based treatments, pulmonary diseases, Antisense Oligonucleotide, inhalation delivery, clinical-stage, Cystic Fibrosis, Idiopathic Pulmonary Fibrosis, biotechnology, drug development, non-invasive therapy.

Company overview

Splisense company information

The essential company record, classifications and operating signals in one place.

Status
Operational
Founded
2016
Headquarters
Jerusalem, Israel
Employees
16
Open positions
None listed
Dealroom signal
42.8
client focusb2btechnologyDeep Techsub industryBioTechnologybusiness modelManufacturingindustryHealthsectorBiotechnologysectorSpinoutsectorDiseasesectorBiotech and PharmasectorHard TechsectorDT and LSsectorscience-based

Valuation & funding

Splisense funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
GRANTOther financing Jun 2026 $13M Cystic Fibrosis Foundation
SERIES BEquity / VC May 2021 $29M $114M Biotel Limited · OrbiMed · Israel Biotech Fund · Cystic Fibrosis Foundation
SPINOUTOther financing Jan 2016 $0 The Hebrew University of Jerusalem · Yissum Research Development
SEEDEquity / VC Jan 2016 $0 Integra Holdings
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Financials

Workforce over time

Available workforce history. Financial fields without reported data are omitted.

YearEmployees
2026 16
2025 16
2024 15
2023 15
2022 12
2021 7
Company filings, research estimates and Dealroom dataOpen the full financial model →

Growth signals

Splisense website traffic

Latest recorded traffic for Splisense is 2.6K monthly website visits, up 23.8% over the last three months. Splisense's team grew 0% over the past year.

Latest monthly visits2.6K 3-month web change+23.8% 1-year team growth0%
Monthly website visits33 observations · Oct 2020–Jul 2026
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Comparisons

Splisense compared with similar companies

Dealroom’s weighted taxonomy model identifies the closest operating peers. Company identity and context stay open; selected comparison metrics preview what is available in the platform.

Showing 8 of the closest matchesCompare every metric →

Talent graph

Splisense's talent

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Team profiled 3 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 1 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

7 investors on Splisense's cap table

Sourced from Dealroom's funding and investor records. Investor profile links are shown where available.

Seed 1 investor entered at this stage
Integra Holdings
Series A 4 investors entered at this stage
Cystic Fibrosis Foundation
Biotel Limited
OrbiMed
Israel Biotech Fund
Other known 2 additional known investors
The Hebrew University of Jerusalem
Yissum Research Development

Global footprint

Where Splisense has talent and traffic

Workforce by country
2 countries with
team presence
🇮🇱 Israel46.1%
🇺🇸 United States7.7%
2 countries shown

In the news

Latest news about Splisense

Recent press, funding announcements, and product moves mentioning Splisense — open to read from the original sources.

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Market sentiment

What the market is saying about Splisense

An AI-synthesized read of the highest-engagement posts about Splisense on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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