S
SiSaf
Biotech & Life Sciences · Guildford, United Kingdom · Founded 2008
Advancing RNA Therapeutics MoreLess
SiSaf is a biopharmaceutical company founded in 2006 by Dr. Suzanne Saffie-Siebert, a nanoparticle scientist with over 25 years of experience in the pharmaceutical industry.
Dr. Saffie-Siebert's journey as an entrepreneur is deeply connected to her scientific expertise. She is the inventor of the company's proprietary Bio-Courier technology, a drug delivery platform based on silicon-stabilized liposomes. This technology is designed to overcome the challenges of delivering RNA-based therapies to specific cells in the body.
SiSaf's business model is focused on the development of RNA therapeutics for rare genetic disorders. The company leverages its Bio-Courier platform to create a pipeline of treatments for these diseases. SiSaf operates in the biopharmaceutical market, collaborating with other companies and research institutions to advance its therapeutic programs. The company generates revenue through a combination of research and development collaborations, licensing agreements, and the future commercialization of its products.
The company's core product is its Bio-Courier technology. This platform utilizes silicon-stabilized liposomes to encapsulate and protect RNA molecules, ensuring their safe and effective delivery to target cells. The benefits of this technology include improved stability, reduced toxicity, and enhanced therapeutic efficacy of RNA-based drugs. A key selling point of the Bio-Courier platform is its potential to enable the development of treatments for a wide range of rare genetic diseases that are currently untreatable.
Keywords: biopharmaceutical, drug delivery, RNA therapeutics, rare genetic disorders, silicon-based, liposomes, gene therapy, nanomedicine, drug development, clinical trials
Company overview
SiSaf company information
The essential company record, classifications and operating signals in one place.
- Status
- Operational
- Founded
- 2008
- Headquarters
- Guildford, United Kingdom
- Employees
- 17
- Open positions
- None listed
- Dealroom signal
- 67.3
Valuation & funding
SiSaf funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| SERIES B✓Equity / VC | Nov 2020 | $13M | $53M | Vickers Venture Partners · Future Fund | — |
| SERIES B✓Equity / VC | May 2018 | $4.3M | $17M | Vickers Venture Partners · Innovation Ulster · Invest Northern Ireland | ↗ |
| SERIES A✓Equity / VC | Sep 2016 | $3.5M | $14M | Vickers Venture Partners | — |
| GRANT✓Other financing | Jan 2016 | $363K | — | Undisclosed | — |
| SEED✓Equity / VC | Oct 2013 | $660K | $2.6M | SVG Partners | — |
| SPINOUT✓Other financing | Jan 2008 | Ulster University | — |
Financials
Workforce over time
Available workforce history. Financial fields without reported data are omitted.
| Year | Employees |
|---|---|
| 2026 | 17 |
| 2025 | 22 |
| 2024 | 22 |
| 2023 | 26 |
| 2022 | 26 |
| 2021 | 22 |
| 2020 | 16 |
Growth signals
SiSaf website traffic
Latest recorded traffic for SiSaf is 530 monthly website visits, down 33.8% over the last three months. SiSaf's team declined 22.7% over the past year.
Comparisons
SiSaf compared with similar companies
Dealroom’s weighted taxonomy model identifies the closest operating peers. Company identity and context stay open; selected comparison metrics preview what is available in the platform.
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RenovosNanoclay gel platform for regenerative medicine therapeutics |
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Sentinel OncologyTargeted oncology candidate drugs for brain tumours |
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MironidSmall molecule therapeutics for hereditary kidney disease |
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Talent graph
SiSaf's talent
Source: Dealroom Talent Intelligence.
Investors
7 investors on SiSaf's cap table
Sourced from Dealroom's funding and investor records.







Global footprint
Where SiSaf has talent and traffic
team presence
In the news
Latest news about SiSaf
Recent press, funding announcements, and product moves mentioning SiSaf — open to read from the original sources.
Market sentiment
What the market is saying about SiSaf
An AI-synthesized read of the highest-engagement posts about SiSaf on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.
Reading the room on X — pulling top posts and synthesizing themes…
Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour
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