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Siren Biotechnology

Biotech & Life Sciences · San Francisco, United States · Founded 2020

Combines AAV gene therapy and cytokine immunotherapy to revolutionize cancer treatment MoreLess

Siren Biotechnology is a pioneering startup focused on revolutionizing cancer treatment through innovative therapies. The company is at the forefront of combining two advanced therapeutic technologies: AAV (Adeno-Associated Virus) gene therapy and cytokine immunotherapy. This unique combination aims to create a powerful new treatment to combat cancer, particularly targeting brain and eye tumors, which are notoriously difficult to treat with existing methods.

Siren Biotechnology operates in the biopharmaceutical market, specifically within the niche of cancer therapeutics. The company serves a diverse range of clients, including healthcare providers, research institutions, and ultimately, cancer patients who are in dire need of more effective treatment options. Their primary goal is to address the significant unmet medical needs in the oncology sector by developing therapies that can overcome the limitations of past treatments.

The business model of Siren Biotechnology is centered around research and development (R&D) of their proprietary AAV immuno gene therapy. They invest heavily in scientific research to advance their treatment modalities from the lab to clinical trials, and eventually to market. The company generates revenue through a combination of funding from venture capital, partnerships with pharmaceutical companies, and potentially, future sales of their approved therapies.

Siren Biotechnology makes money by securing investments from venture capital firms, forming strategic partnerships with larger pharmaceutical companies, and through the eventual commercialization of their therapies. By bringing their innovative treatments to market, they aim to not only improve patient outcomes but also achieve financial sustainability and growth.

In summary, Siren Biotechnology is dedicated to changing the landscape of cancer treatment through cutting-edge AAV gene therapy and cytokine immunotherapy. Their focus on brain and eye tumors positions them uniquely in the oncology market, with a strong emphasis on R&D and strategic partnerships to drive their business forward.

Keywords: Cancer, AAV gene therapy, Cytokine immunotherapy, Brain tumors, Eye tumors, Oncology, Biopharmaceutical, R&D, Innovative therapies, Strategic partnerships.

Company overview

Siren Biotechnology company information

The essential company record, classifications and operating signals in one place.

Status
Operational
Founded
2020
Headquarters
San Francisco, United States
Employees
10
Open positions
None listed
Dealroom signal
71.4
client focusb2bsub industryBioTechnologybusiness modelManufacturingindustryHealthsectorBiotechnologysectorSpinoutsectorBiotech and PharmasectorWoman FoundersectorDT and LSsectorscience-based

Valuation & funding

Siren Biotechnology funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
GRANTOther financing Jun 2026 $8M California Institute for Regenerative Medicine
SEEDEquity / VC Apr 2024 $20M $78M Undisclosed
GRANTOther financing Nov 2023 $4M California Institute for Regenerative Medicine
SEEDEquity / VC May 2023 $0 Innovation Endeavors · Civilization Ventures · Lux Capital · Savantus Ventures
SPINOUTOther financing Jan 2020 $0 University of California, San Francisco
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Financials

Workforce over time

Available workforce history. Financial fields without reported data are omitted.

YearEmployees
2026 10
2025 11
2024 9
2023 4
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Growth signals

Siren Biotechnology website traffic

Latest recorded traffic for Siren Biotechnology is 2.9K monthly website visits, down 3.3% over the last three months. Siren Biotechnology's team declined 9.1% over the past year.

Latest monthly visits2.9K 3-month web change-3.3% 1-year team growth-9.1%
Monthly website visits39 observations · May 2023–Jul 2026
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Hiring

Open positions at Siren Biotechnology

Current openings linked to this company in Dealroom.

1 distinct opening shownExplore hiring signals →

Comparisons

Siren Biotechnology compared with similar companies

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Talent graph

Siren Biotechnology's talent

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Team profiled 2 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 1 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

9 investors on Siren Biotechnology's cap table

Sourced from Dealroom's funding and investor records. Investor profile links are shown where available.

Seed 5 investors entered at this stage
Innovation Endeavors
Civilization Ventures
Lux Capital
Savantus Ventures
California Institute for Regenerative Medicine
Other known 4 additional known investors
University of California, San Francisco
Carnrite Ventures
Hawktail
NZVC

Global footprint

Where Siren Biotechnology has talent and traffic

Workforce by country
1 countries with
team presence
🇺🇸 United States100%
1 country shown

In the news

Latest news about Siren Biotechnology

Recent press, funding announcements, and product moves mentioning Siren Biotechnology — open to read from the original sources.

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Market sentiment

What the market is saying about Siren Biotechnology

An AI-synthesized read of the highest-engagement posts about Siren Biotechnology on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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