S
Siren Biotechnology
Biotech & Life Sciences · San Francisco, United States · Founded 2020
Combines AAV gene therapy and cytokine immunotherapy to revolutionize cancer treatment MoreLess
Siren Biotechnology is a pioneering startup focused on revolutionizing cancer treatment through innovative therapies. The company is at the forefront of combining two advanced therapeutic technologies: AAV (Adeno-Associated Virus) gene therapy and cytokine immunotherapy. This unique combination aims to create a powerful new treatment to combat cancer, particularly targeting brain and eye tumors, which are notoriously difficult to treat with existing methods.
Siren Biotechnology operates in the biopharmaceutical market, specifically within the niche of cancer therapeutics. The company serves a diverse range of clients, including healthcare providers, research institutions, and ultimately, cancer patients who are in dire need of more effective treatment options. Their primary goal is to address the significant unmet medical needs in the oncology sector by developing therapies that can overcome the limitations of past treatments.
The business model of Siren Biotechnology is centered around research and development (R&D) of their proprietary AAV immuno gene therapy. They invest heavily in scientific research to advance their treatment modalities from the lab to clinical trials, and eventually to market. The company generates revenue through a combination of funding from venture capital, partnerships with pharmaceutical companies, and potentially, future sales of their approved therapies.
Siren Biotechnology makes money by securing investments from venture capital firms, forming strategic partnerships with larger pharmaceutical companies, and through the eventual commercialization of their therapies. By bringing their innovative treatments to market, they aim to not only improve patient outcomes but also achieve financial sustainability and growth.
In summary, Siren Biotechnology is dedicated to changing the landscape of cancer treatment through cutting-edge AAV gene therapy and cytokine immunotherapy. Their focus on brain and eye tumors positions them uniquely in the oncology market, with a strong emphasis on R&D and strategic partnerships to drive their business forward.
Keywords: Cancer, AAV gene therapy, Cytokine immunotherapy, Brain tumors, Eye tumors, Oncology, Biopharmaceutical, R&D, Innovative therapies, Strategic partnerships.
Company overview
Siren Biotechnology company information
The essential company record, classifications and operating signals in one place.
- Status
- Operational
- Founded
- 2020
- Headquarters
- San Francisco, United States
- Employees
- 10
- Open positions
- None listed
- Dealroom signal
- 71.4
Valuation & funding
Siren Biotechnology funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| GRANT✓Other financing | Jun 2026 | $8M | — | California Institute for Regenerative Medicine | ↗ |
| SEED✓Equity / VC | Apr 2024 | $20M | $78M | Undisclosed | ↗ |
| GRANT✓Other financing | Nov 2023 | $4M | — | California Institute for Regenerative Medicine | ↗ |
| SEEDEquity / VC | May 2023 | $0 | — | Innovation Endeavors · Civilization Ventures · Lux Capital · Savantus Ventures | ↗ |
| SPINOUT✓Other financing | Jan 2020 | $0 | — | University of California, San Francisco | — |
Financials
Workforce over time
Available workforce history. Financial fields without reported data are omitted.
| Year | Employees |
|---|---|
| 2026 | 10 |
| 2025 | 11 |
| 2024 | 9 |
| 2023 | 4 |
Growth signals
Siren Biotechnology website traffic
Latest recorded traffic for Siren Biotechnology is 2.9K monthly website visits, down 3.3% over the last three months. Siren Biotechnology's team declined 9.1% over the past year.
Hiring
Open positions at Siren Biotechnology
Current openings linked to this company in Dealroom.
Comparisons
Siren Biotechnology compared with similar companies
Dealroom’s weighted taxonomy model identifies the closest operating peers. Company identity and context stay open; selected comparison metrics preview what is available in the platform.
Talent graph
Siren Biotechnology's talent
Source: Dealroom Talent Intelligence.
Global footprint
Where Siren Biotechnology has talent and traffic
team presence
In the news
Latest news about Siren Biotechnology
Recent press, funding announcements, and product moves mentioning Siren Biotechnology — open to read from the original sources.
Market sentiment
What the market is saying about Siren Biotechnology
An AI-synthesized read of the highest-engagement posts about Siren Biotechnology on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.
Reading the room on X — pulling top posts and synthesizing themes…
Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour
See Siren Biotechnology’s full profile on Dealroom
Request a free trial to see the complete deal history, financials, people graph and growth signals.
Takes under a minute. Already use Dealroom? Log in.















