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Orthox

Biotech & Life Sciences · Milton, United Kingdom · Founded 2008

Developes tissue regenerative implants which enable patients to return to a fully active, pain-free lifestyle MoreLess

Orthox is a pioneering company in the life sciences sector, focusing on innovative solutions for knee injuries. The company operates in the medical technology market, specifically targeting patients with cartilage and meniscus injuries in the knee. These injuries can lead to severe disability and often result in the need for total knee replacement, a costly and invasive procedure. Orthox aims to provide a less invasive alternative through its lead product, Cartilage, a natural implant designed to restore knee function and promote the body's own healing processes.

Orthox primarily serves patients who are at risk of or are already experiencing knee joint deterioration. This includes both young and older individuals who suffer from knee injuries that could lead to osteoarthritis. The company's products are particularly beneficial for those who want to avoid the limitations and risks associated with total knee replacement surgery.

The business model of Orthox revolves around the development, clinical testing, and eventual commercialization of its knee cartilage repair products. The company has secured significant funding from various prestigious sources, including the EU Horizon 2020 programme and the NIHR i4i programme. These funds are being used to advance the clinical strategy and bring their innovative solutions to market.

Orthox generates revenue through the sale of its medical implants once they pass clinical trials and receive regulatory approval. The company also benefits from grants and awards that support its research and development activities. By focusing on a niche but growing market, Orthox aims to address a critical medical need and reduce the number of total knee replacement surgeries performed annually.

In summary, Orthox is a forward-thinking company dedicated to improving knee health through natural, resilient implants that restore function and promote healing. Their innovative approach and strong financial backing position them well in the competitive medical technology market.

Keywords: Orthox, knee injuries, cartilage repair, medical implants, life sciences, osteoarthritis, clinical trials, EU Horizon 2020, NIHR i4i, healthcare innovation.

Company overview

Orthox company information

The essential company record, classifications and operating signals in one place.

Status
Operational
Founded
2008
Headquarters
Milton, United Kingdom
Employees
9
Open positions
None listed
Dealroom signal
58.9
client focusb2csub industryPharmaceuticalsub industryBioTechnologysub industryMedical Devicesbusiness modelManufacturingindustryHealthsectorDeveloper Toolssectormedical implantssectorTissue EngineeringsectorSpinoutsectorSustainable Development GoalssectorEICsectorStart-Up Rescue Instrument (EIT Health)sectorStart-Up Rescue Instrument 2020 (EIT Health)

Valuation & funding

Orthox funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SERIES AEquity / VC Aug 2022 $13M $50M Oxford Technology · Additio Investment Group · Parkwalk Advisors
SERIES AEquity / VC Feb 2022 $4.2M $17M Parkwalk Advisors · Oxford Technology · Perivoli Innovations · Additio Investment Group
SUPPORT PROGRAMOther financing Nov 2020 $550K EIT Health
GRANTOther financing Jul 2020 $2.8M Undisclosed
GRANTOther financing Feb 2020 $437K Undisclosed
GRANTOther financing Oct 2019 European Innovation Council
GRANTOther financing Jan 2019 Undisclosed
GRANTOther financing Dec 2018 European Innovation Council
EARLY VCEquity / VC Aug 2018 AtmosClear Investments
SERIES AEquity / VC Apr 2016 Parkwalk Advisors
Showing 10 recorded eventsUnlock the complete deal history →

Financials

Revenue, earnings and profit over time

Reported history and available estimates. Estimated years are marked “E”; sparse fields are left blank rather than inferred.

YearEBITDAMarginProfitMargin
2026 −$384K −$1.3M
2025 −$384K −$1.3M
2024 −$384K −$1.3M
2023 −$384K
2022 −$384K
2021 −$384K
2020 −$384K
Company filings, research estimates and Dealroom dataOpen the full financial model →

Growth signals

Orthox website traffic

Latest recorded traffic for Orthox is 3.3K monthly website visits, up 153.8% over the last three months. Orthox's team grew 0% over the past year.

Latest monthly visits3.3K 3-month web change+153.8% 1-year team growth0%
Monthly website visits63 observations · Jul 2017–Jul 2026
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Comparisons

Orthox compared with similar companies

Dealroom’s weighted taxonomy model identifies the closest operating peers. Company identity and context stay open; selected comparison metrics preview what is available in the platform.

Showing 8 of the closest matchesCompare every metric →

Talent graph

Orthox's talent

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Team profiled 5 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

11 investors on Orthox's cap table

Sourced from Dealroom's funding and investor records.

Seed 1 investor entered at this stage
European Innovation Council
Series A 5 investors entered at this stage
Parkwalk Advisors
AtmosClear Investments
Oxford Technology
Perivoli Innovations
Additio Investment Group
Other known 5 additional known investors
University of Oxford
EIT Health
Moti Vyas
Oxford Investment Consultants
University of Bristol Enterprise Fund

Global footprint

Where Orthox has talent and traffic

Workforce by country
1 countries with
team presence
🇬🇧 United Kingdom100%
1 country shown

In the news

Latest news about Orthox

Recent press, funding announcements, and product moves mentioning Orthox — open to read from the original sources.

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Market sentiment

What the market is saying about Orthox

An AI-synthesized read of the highest-engagement posts about Orthox on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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