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Heron Therapeutics
Postoperative pain and oncology care therapeutic solutions
About Heron Therapeutics
The story of what we now know as Heron Therapeutics begins not in the 2000s, but back in 1983, when it was incorporated as A.P. Pharma, Inc. For decades, the specialty pharmaceutical company worked on developing products using a proprietary drug delivery platform. This technology, called Biochronomer, was designed to improve injectable drugs by allowing them to be administered less frequently. The company's major turning point came in the early 2010s. In August 2013, with Barry Quart at the helm as CEO, the company announced a significant corporate rebranding. It filed to list on the NASDAQ and planned to change its name from A.P. Pharma to Heron Therapeutics, a move that became official in January 2014. This wasn't just a name change; it signaled a strategic refocus on developing and commercializing best-in-class therapies, particularly in oncology and postoperative care. This new chapter saw Heron transition from a development-stage company to a commercial one. It launched key products for managing chemotherapy-induced nausea and vomiting (CINV), such as SUSTOL and CINVANTI. A major milestone was the 2021 FDA approval of ZYNRELEF, a non-opioid treatment for postoperative pain. Heron is now a publicly-traded company on the NASDAQ under the ticker HRTX. Through strategic rebranding and a focused execution on unmet needs in patient care, the company carved out its modern identity.
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Funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| POST IPO CONVERTIBLE✓Other financing | Aug 2025 | $125M | — | Undisclosed | ↗ |
| POST IPO DEBT✓Debt | Aug 2025 | $110M | — | Hercules Capital | ↗ |
Financials
Revenue, earnings and other financial measures where available. Years marked “E” are estimates.
Growth signals
Latest recorded traffic for Heron Therapeutics is 79K monthly website visits. Heron Therapeutics's team declined 42.4% over the past year.
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Investments and acquisitions
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Heron Therapeutics in the Cary ecosystem
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Investors
From Dealroom's funding and investor records, grouped by the round each investor first entered.
Series B and later1 investor entered at this stage
Hercules Capital
Other known investors6 additional known investors
- BRBroadfin
Clearline Capital
Deep Track Capital
Great Point Partners- RMRubric Capital Management
Velan Capital
Source: Dealroom Talent Intelligence.
Global footprint
team presence
Market sentiment
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