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BioCryst Pharmaceuticals

Biotech & Life Sciences · Durham, United States · Founded 1986 · IPO 1994

BioCryst has over 80 employees spread across their two locations in Birmingham, Alabama and Durham, North Carolina MoreLess

BioCryst Pharmaceuticals focuses on developing innovative oral drugs for rare diseases, with a particular emphasis on hereditary angioedema (HAE). The company leverages a combination of traditional cell biology and medicinal chemistry to create synthetic compounds that target specific proteins to combat diseases. BioCryst serves patients suffering from rare conditions, aiming to enhance their ability to engage in everyday activities. Operating in the biopharmaceutical market, BioCryst's business model revolves around research and development, clinical trials, and eventual commercialization of its drug pipeline. Revenue is generated through the sale of approved drugs and potential licensing agreements. The company's commitment to scientific excellence and patient needs drives its mission to deliver extraordinary treatments. Keywords: rare diseases, oral drugs, hereditary angioedema, synthetic compounds, protein targets, biopharmaceutical, clinical trials, drug pipeline, patient-focused, scientific excellence.

Valuation $3.02B
Revenue $702M
Total funding $10–50M

Company overview

BioCryst Pharmaceuticals company information

The essential company record, classifications and operating signals in one place.

Status
Operational
Founded
1986
Headquarters
Durham, United States
Employees
617
Open positions
17
Dealroom signal
40.4
Investment activity
1 companies · latest Oct 2025
Capital deployed
Preferred round
ACQUISITION
client focusb2bsub industryBioTechnologybusiness modelManufacturingindustryHealthsectorBiotechnologysectorobservatoire healthtech

Valuation & funding

BioCryst Pharmaceuticals funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
POST IPO DEBTDebt Apr 2023 $450M Pharmakon Holdings
POST IPO EQUITYOther financing Nov 2021 $350M OMERS Capital Markets · Royalty Pharma
POST IPO DEBTDebt Dec 2020 $200M Royalty Pharma · Athyrium Capital Management
POST IPO EQUITYOther financing Dec 2020 $125M Royalty Pharma
POST IPO EQUITYOther financing May 2020 $82M Undisclosed
POST IPO EQUITYOther financing Nov 2019 Undisclosed
POST IPO DEBTDebt Feb 2019 Midcap Financial
GRANTOther financing Sep 2018 Undisclosed
POST IPO EQUITYOther financing Sep 2017 Undisclosed
POST IPO DEBTDebt Sep 2016 Midcap Financial
Showing 10 recorded eventsUnlock the complete deal history →

Financials

Revenue, earnings and profit over time

Reported history and available estimates. Estimated years are marked “E”; sparse fields are left blank rather than inferred.

YearRevenueGrowthEBITDAMarginProfitMarginR&D
2026 $702M -19.7% −$498M -70.9% −$579M -82.4% $166M
2025 $875M +94.1% $365M 41.7% $264M 30.2% $166M
2024 $451M +36% $13M 3% −$89M -19.7% $175M
2023 $331M +22.4% −$86M -26% $217M
2022 $271M +72.3% −$143M -52.9%
2021 $157M +782.4% −$178M -113%
2020 $18M −$165M -928.2%
Company filings, research estimates and Dealroom dataOpen the full financial model →

Growth signals

BioCryst Pharmaceuticals website traffic

Latest recorded traffic for BioCryst Pharmaceuticals is 27K monthly website visits, up 17.4% over the last three months. BioCryst Pharmaceuticals's team grew 14.5% over the past year.

Latest monthly visits27K 3-month web change+17.4% 1-year team growth+14.5%
Monthly website visits42 observations · Apr 2016–Mar 2021
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Comparisons

BioCryst Pharmaceuticals compared with similar companies

Dealroom’s weighted taxonomy model identifies the closest operating peers. Company identity and context stay open; selected comparison metrics preview what is available in the platform.

Showing 8 of the closest matchesCompare every metric →

Capital deployed

BioCryst Pharmaceuticals investments and acquisitions

Recent portfolio relationships for companies that also act as investors or acquirers.

Talent graph

BioCryst Pharmaceuticals's talent

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Team profiled 20 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 5 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

8 investors on BioCryst Pharmaceuticals's cap table

Sourced from Dealroom's funding and investor records. Investor profile links are shown where available.

Seed 1 investor entered at this stage
US National Institute of Allergy and Infectious Diseases
Series B+ 5 investors entered at this stage
Midcap Financial
Royalty Pharma
Athyrium Capital Management
OMERS Capital Markets
Pharmakon Holdings
Other known 2 additional known investors
Kleiner Perkins
US Biomedical Advanced Research and Development Authority

Global footprint

Where BioCryst Pharmaceuticals has talent and traffic

Workforce by country
17 countries with
team presence
🇺🇸 United States81.2%
🇬🇧 United Kingdom3.3%
🇨🇦 Canada2.9%
🇪🇸 Spain2.5%
🇫🇷 France1.9%
Top 5 of 17 shown

In the news

Latest news about BioCryst Pharmaceuticals

Recent press, funding announcements, and product moves mentioning BioCryst Pharmaceuticals — open to read from the original sources.

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Market sentiment

What the market is saying about BioCryst Pharmaceuticals

An AI-synthesized read of the highest-engagement posts about BioCryst Pharmaceuticals on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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