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Allyx Therapeutics

Biotech & Life Sciences · New Haven, United States · Founded 2018

Innovative oral therapies preserving synapses for neurodegenerative disease patients MoreLess

Allyx Therapeutics is a biotech startup focused on developing groundbreaking therapies to preserve and protect synapses for individuals suffering from neurodegenerative diseases. The company’s lead compound, ALX 001, is a first-in-class oral therapy that targets the mGluR5 receptor, a critical component in preventing amyloid beta-induced neuronal damage. Founded in 2019 by Yale scientists, biopharma industry veterans, and venture capitalists, Allyx Therapeutics operates in the neurodegenerative disease market, primarily serving patients and healthcare providers. The company is currently in the Series A funding stage and has successfully utilized both public and private non-dilutive funding sources, including grants from the National Institutes of Health (NIH). Allyx Therapeutics generates revenue through the development and eventual commercialization of its proprietary therapies. The company is actively engaged in clinical research, with ongoing Phase 1b trials for ALX 001, and aims to expand its pipeline to address additional neurodegenerative conditions.

Keywords: neurodegenerative, synapses, mGluR5, amyloid beta, oral therapy, Phase 1b, biotech startup, Yale scientists, NIH funding, Series A.

Company overview

Allyx Therapeutics company information

The essential company record, classifications and operating signals in one place.

Status
Operational
Founded
2018
Headquarters
New Haven, United States
Employees
5
Open positions
None listed
Dealroom signal
56.9
client focusb2bsub industryPharmaceuticalsub industryBioTechnologyindustryHealthsectorBiotechnologysectorSpinoutsectorBiotech and PharmasectorDT and LSsectorscience-based

Valuation & funding

Allyx Therapeutics funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SERIES AEquity / VC May 2025 $27M $106M Bristol-Myers Squibb · Canaan Partners Israel
GRANTOther financing Oct 2024 $3.3M National Institutes of Health
EARLY VCEquity / VC Feb 2023 $2.3M $9.2M Undisclosed
EARLY VCEquity / VC Jun 2021 $7.6M $30M Undisclosed
OtherOther financing Jan 2021 $0 Life Science Angels
CONVERTIBLEEquity / VC Apr 2019 Connecticut Innovations
SPINOUTOther financing Jan 2019 Yale University
Showing 7 recorded eventsUnlock the complete deal history →

Financials

Workforce over time

Available workforce history. Financial fields without reported data are omitted.

YearEmployees
2026 5
2025 5
2024 4
2023 3
2022 3
Company filings, research estimates and Dealroom dataOpen the full financial model →

Growth signals

Allyx Therapeutics website traffic

Latest recorded traffic for Allyx Therapeutics is 1.3K monthly website visits, down 7.1% over the last three months. Allyx Therapeutics's team grew 0% over the past year.

Latest monthly visits1.3K 3-month web change-7.1% 1-year team growth0%
Monthly website visits35 observations · Nov 2022–Jun 2026
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Comparisons

Allyx Therapeutics compared with similar companies

Dealroom’s weighted taxonomy model identifies the closest operating peers. Company identity and context stay open; selected comparison metrics preview what is available in the platform.

Showing 8 of the closest matchesCompare every metric →

Talent graph

Allyx Therapeutics's talent

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Team profiled 5 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

9 investors on Allyx Therapeutics's cap table

Sourced from Dealroom's funding and investor records. Investor profile links are shown where available.

Seed 1 investor entered at this stage
National Institutes of Health
Series A 3 investors entered at this stage
Connecticut Innovations
Bristol-Myers Squibb
Canaan Partners Israel
Other known 5 additional known investors
Life Science Angels
Yale University
Harbor Street Ventures
Small Business Innovation Research
Yale Ventures

Global footprint

Where Allyx Therapeutics has talent and traffic

Workforce by country
1 countries with
team presence
🇺🇸 United States100%
1 country shown

In the news

Latest news about Allyx Therapeutics

Recent press, funding announcements, and product moves mentioning Allyx Therapeutics — open to read from the original sources.

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Market sentiment

What the market is saying about Allyx Therapeutics

An AI-synthesized read of the highest-engagement posts about Allyx Therapeutics on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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