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St. Louis

Metro area · United States · Pop. 2.8M · WithinWorldNorth AmericaUnited StatesSt. Louis

Startup funnel

St. Louis's startup funnel

Companies headquartered in St. Louis at each stage today, by total VC raised. Hover or tap a bar for the split.

307
Startups
$100K–15M raised

133 pre-seed · 92 seed · 82 Series A

69
Breakouts
$15–100M raised

49 Series B · 20 Series C

16
Scaleups
$100M+ raised

11 Mega · 5 Mega+

5
Unicorns and/or $100M+ revenue

4 valued at $1B+ · 4 with $100M+ revenue · 3 both

Source: Dealroom.co

Quarterly report

St. Louis's latest quarter in venture capital

Venture capital raised by St. Louis-headquartered companies each quarter since 2020, split by round size, with detail on the latest complete quarter.

Latest complete quarter

 

Loading VC raised by St. Louis-headquartered companies…

Enterprise value

How much St. Louis’s VC-backed companies are worth

Combined enterprise value of VC-backed companies headquartered in St. Louis, founded since 1990 and still operating, at the end of each year. Companies stay in the total after they list or are acquired.

VC investment

How much venture capital flows into St. Louis

VC investment into St. Louis-headquartered, VC-backed companies, broken down by round size, company location, sector and funding stage.

Largest rounds

Largest funding rounds in St. Louis

A live treemap of the largest VC rounds. Each cell is one round into St. Louis-headquartered companies, grouped by Dealroom sector.

Largest rounds in St. Louis - 2026

Every $15M+ VC round into St. Louis-headquartered companies in 2026, grouped by Dealroom sector.
- rounds · - raised
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Academia

St. Louis's academic flywheel

Companies founded by university alumni or spun out of research, plus the institutions producing the most founders tied to St. Louis.

University-linked startup formation
63
University spinouts
651
Total alumni-founded companies
374
Of which startups (<$15M raised)
197
Breakouts ($15M-100M)
80
Scaleups ($100M+)

Location comparison

How St. Louis stacks up

Compare St. Louis with peers from the same country (United States) — switch between combined EV, EV growth, and a growth × size view. Expand the table for the full ranking.

$62B
$60.6B
$60.5B
$53B
$43.5B
$40.8B
$38B
St. Louis
$18.1B

Combined enterprise value of each ecosystem.

Get the full St. Louis ecosystem on Dealroom

Live company-by-company deal flow, full cap tables, founder pedigrees, hiring signals and revenue trajectories.